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New discovery helps build climate resilience in global food systems

Breakthrough research from Carlsberg Research Laboratory reveals genetic key to tackling billion-dollar crop losses linked to climate change.
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13 November 2025

An international research team led by the Carlsberg Research Laboratory has identified a crucial gene that could help protect staple crops from the increasing risks posed by climate change. The findings, published in Science, offer a new approach to reduce pre-harvest sprouting – a phenomenon triggered by unpredictable weather and responsible for billions of dollars in crop losses globally each year.

Pre-harvest sprouting (PHS) occurs when cereal grains such as barley, wheat or rice begin to germinate prematurely on the plant due to untimely rainfall or humidity. Once sprouting starts, grains lose processing quality and become more vulnerable to spoilage and fungal contamination, leaving them unsuitable for both human consumption and animal feed.

At the heart of the new discovery is the gene MKK3, which the research team found plays a central role in controlling seed dormancy. By mapping the diversity of MKK3 gene variants in barley from across the world and conducting extensive field trials, the researchers have created a roadmap for breeders to develop crop varieties that are better adapted to increasingly erratic weather patterns.

“Our work shows how centuries of farming and climate adaptation have shaped the genetic landscape of this vital crop and provides a roadmap for breeders to balance dormancy and sprouting risk – helping farmers everywhere grow better crops, even as weather becomes more unpredictable,” Christoph Dockter, Head of Cereal Crop Development at the Carlsberg Research Laboratory.

The study combines cutting-edge genetic analysis with practical field data and offers insights relevant far beyond barley. It reflects a growing understanding of how climate adaptation strategies must be embedded at the genetic level to build robust food systems.

Key findings

  • Genetic insights: The MKK3 gene affects how long seeds stay dormant, directly influencing the risk of premature germination.
  • Global mapping: Researchers identified regional gene variations shaped by centuries of local adaptation, offering guidance for climate-smart breeding.
  • Field-tested impact: Multi-year field trials demonstrate how targeted breeding can enhance resilience without compromising yield.
Read the full press release

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